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Key Item

Road Map to a Comprehensive Healthcare-Associated Infection (HAI) Prevention Program. See the antimicrobial stewardship program section. Complete the HAI road map audit checklist prior to beginning any of the gap analyses.

Antimicrobial Stewardship - HAI prevention strategies

An antimicrobial stewardship program (ASP) is a building block for healthcare-associated infection (HAI) prevention.

The practices in the Road Map to a Comprehensive Healthcare-Associated Infection (HAI) Prevention Program, including the antimicrobial stewardship program section, guide organizations in developing the infrastructure necessary to support and sustain infection prevention best practices.

Sample Tools


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You'll notice that some sections of this website lack supporting materials. We're asking CHAIN participants to share tools and resources to add to this site. Sharing knowledge will help us all provide better care to people in Minnesota.

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Antimicrobial Stewardship Driver Diagram and Change Package. A change package from the Institute for Health Care Improvement. (12-page PDF) 

Antimicrobial Stewardship Toolkit. This toolkit from the American Hospital Association contains resources for developing or enhancing a successful Antimicrobial Stewardship Program.

The California Antimicrobial Stewardship Program Initiative. Description of  the initiative from the California Department of Public Health. Viewed 08/31/12.

Checklist for Core Elements of Hospital Antibiotic Stewardship Programs. This checklist from the Centers for Disease Control and Prevention is a companion to Core Elements of Hospital Antibiotic Stewardship Programs. This checklist should be used to systematically assess key elements and actions to ensure optimal antibiotic prescribing and limit overuse and misuse of antibiotics in hospitals. (4-page PDF)

Core Elements of Hospital Antibiotic Stewardship Programs. This document from the Centers for Disease Control and Prevention summarizes core elements of successful hospital antibiotic stewardship programs. (25-page PDF)

Get Smart for Healthcare: Know When Antibiotics Work. A PowerPoint presentation from the National Center for Emerging and Zoonotic Infectious Diseases.  (42-page PPT)

Getting Started. Lists the key literature mentioned in the ASP building blocks section. (2-page Word doc)

The Road Map to a Comprehensive Healthcare-Associated Infections (HAI) Prevention Program. Provides evidence-based recommendations and standards for Minnesota hospitals to develop comprehensive HAI prevention programs. Reflects published literature and guidelines from professional organizations and regulatory agencies, as well as identified best practices. (10-page PDF)

Toolkit for Reduction of Clostridium difficile Infections Through Antimicrobial Stewardship: The Evaluation and Research on Antimicrobial Stewardship's Effect on Clostridium difficile (ERASE C. difficile) Project. This toolkit assists hospital staff and leadership in developing an effective antimicrobial stewardship program with the potential to reduce C. difficile. An antimicrobial stewardship program is a systematic approach to developing coordinated interventions to reduce overuse and inappropriate selection of antibiotics, and to achieve optimal outcomes for patients in cost-efficient ways.

Society for Healthcare Epidemiology of America. Offers resources on antimicrobial stewardship.

Professional Education and Training

A collection of presentations from the October 24. 2013 CHAIN-sponsored Antimicrobial Stewardship Conference that provide examples of a variety of effective strategies for antimicrobial stewardship programs throughout Minnesota.

Antimicrobial Stewardship. Abstract of article from the Wiley Online Library. (3-page PDF)

Antimicrobial Stewardship for the Community Hospital: Practical Tools & Techniques for Implementation. This Centers for Disease Control and Prevention online activity was recorded at a live roundtable discussion of the same name, in Atlanta, Georgia, on August 24, 2010. It contains one introduction module and 9 CME/CE modules.

Antimicrobial Stewardship Toolkit. Best practices from the Greater New York Hospital Association United Health Fund Antimicrobial Stewardship Collaborative. (93-page PDF)



Antibiotic Stewardship Video. Produced by South Dakota Public Television’s medical program, On Call. (56-minute video)

Antimicrobial Stewardship: Why and How. Slides from a CDC presentation describing antibiotic misuse and its implications. (10-page PDF)

Antimicrobial Stewardship–Why We Must, How We Can. Presented on January 16, 2014, by CAPT Arjun Srinivasan, MD. (55-minute webinar)

Infectious Diseases Society of America. Website with policies, facts, and patient stories on antimicrobial resistance. Viewed 08/31/2.

Minimum Antibiotic Stewardship Measures. Article from the Department of Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland. (15-page PDF)

Need and Potential of Antimicrobial Stewardship in Community Hospitals. This article reviews strategies and resources available to community hospitals for improving if, when, and how antimicrobial agents are prescribed and delivered. Oxford Journals, viewed 08/30/12.

Preserving Antibiotic Effectiveness: Everybody’s Responsibility. Ramanan Laxminarayan, director of the Center for Disease Dynamics, Economics & Policy, discusses the urgent need to preserve antibiotics. He highlights the emerging crisis of antibiotic resistance and likens antibiotics to a natural resource―a call to action for concerned consumers, parents, and patients, encouraging everyone to limit their use of antibiotics in order to preserve their effectiveness for future generations.

Results of antimicrobial stewardship studies. From the Society for Healthcare Epidemiology of America. (10-page PDF)

References, Guidelines, Standards

Antimicrobial Stewardship Guidelines and Resources. From the Society for Healthcare Epidemiology of America. Viewed 08/31/12.

Antimicrobial Stewardship Policy Statement. Policy Statement on Antimicrobial Stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Chicago Journals, viewed 08/30/12

Antimicrobial Stewardship Resources Chart. A set of guidelines for establishing an antimicrobial stewardship program from the State of Wisconsin Department of Health Services. (10-page PDF)

Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship. Recommendations by the Infectious Diseases Society of America (IDSA) and the Society for Healthcare Epidemiology of America for developing a program to enhance antimicrobial stewardship in the hospital setting to improve the quality of care. Published in Clinical Infectious Diseases 2007, Jan 15;44(2):159-77. Full text guideline.

Patient Education


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CHAIN is an effort lead by the Association for Professionals in Infection Control and Epidemiology-Minnesota (APIC MN), Minnesota Department of Health, Minnesota Hospital Association, and Stratis Health, which represents Lake Superior Quality Innovation Network in Minnesota.